Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1144919 | 0.87 | MAOA (0.33) | ALOX5ALDH1A1ALOX15TDP1 | |
| SCHEMBL18489034 | 0.80 | ALOX5 (0.34) | ALOX5ALDH1A1 | |
| SCHEMBL30788160 | 0.79 | ALOX5 (0.43) | ALOX5ALDH1A1HPGDALOX15TDP1 | |
| SCHEMBL5771393 | 0.79 | ALOX5 (0.43) | ALOX5ALDH1A1HPGDALOX15TDP1 | |
| SCHEMBL30936097 | 0.79 | ALOX5 (0.56) | ALOX5ADAMTS4ALDH1A1EGFRCA1 | |
| SCHEMBL2197852 | 0.79 | ALOX5 (0.56) | ALOX5ADAMTS4ALDH1A1EGFRCA1 | |
| SCHEMBL31084126 | 0.77 | ALOX5 (0.55) | ALOX5ADAMTS4ALDH1A1EGFRCA1 | |
| SCHEMBL3167772 | 0.69 | ALOX5 (0.40) | ALOX5ALDH1A1EGFRCA2LMNA | |
| SCHEMBL124605 | 0.69 | ALOX5 (0.60) | ALOX5ADAMTS4ALDH1A1EGFRCA1 | |
| SCHEMBL29368510 | 0.69 | ALOX5 (0.60) | ALOX5ADAMTS4ALDH1A1EGFRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654257-B1 | AMINOPYRONES AND THEIR USE AS ATM INHIBITORS | KUDOS PHARM LTD (GB) | 2010-03-17 | — | — | EP | disclosed |