Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31604837 | 0.87 | KMT2A (0.52) | POLBMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL23220454 | 0.80 | POLB (0.83) | POLBGAAMAPTTP53THRB | |
| SCHEMBL29630289 | 0.75 | PTGS2 (0.62) | POLBPTGS2MAPTSMN1; SMN2LMNA | |
| SCHEMBL24470969 | 0.75 | PTGS2 (0.62) | POLBPTGS2MAPTSMN1; SMN2LMNA | |
| SCHEMBL18516741 | 0.75 | PTGS2 (0.76) | POLBGAAPTGS2MAPTSMN1; SMN2 | |
| SCHEMBL31605004 | 0.74 | PTGS2 (0.71) | POLBGAAPTGS2MAPTSMN1; SMN2 | |
| SCHEMBL31604878 | 0.74 | PTGS2 (0.60) | POLBPTGS2MAPTSMN1; SMN2LMNA | |
| SCHEMBL31604825 | 0.74 | ALDH1A1 (0.52) | POLBPTGS2MAPTSMN1; SMN2LMNA | |
| SCHEMBL18516845 | 0.73 | RXFP1 (0.66) | POLBGAAPTGS2MAPTTP53 | |
| SCHEMBL19057913 | 0.73 | MAPT (0.83) | POLBGAAMAPTTP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111414-A1 | TRPM3-MODULATING BENZOFURAN DERIVATIVES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2025-05-30 | — | — | WO | disclosed |