Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 6/20 | 0.52 |
| ▸ | MET | P08581 | 5/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.39 |
| ▸ | AGER | Q15109 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12640059 | 0.81 | RPS6KA5 (0.52) | RPS6KA5METP2RX7RPS6KA4CDC7 | |
| SCHEMBL28180779 | 0.80 | RPS6KA5 (0.47) | RPS6KA5METP2RX7RPS6KA4CDC7 | |
| SCHEMBL14409582 | 0.78 | MET (0.52) | RPS6KA5METP2RX7RPS6KA4CDC7 | |
| SCHEMBL31061608 | 0.77 | CYP11B1 (0.62) | RPS6KA5METP2RX7 | |
| SCHEMBL29997534 | 0.77 | RPS6KA5 (0.47) | RPS6KA5METP2RX7RPS6KA4CDC7 | |
| SCHEMBL18926931 | 0.77 | RPS6KA5 (0.47) | RPS6KA5METP2RX7RPS6KA4CDC7 | |
| SCHEMBL4716978 | 0.77 | CYP11B1 (0.62) | RPS6KA5METP2RX7 | |
| SCHEMBL24437382 | 0.75 | GRIN2B (0.46) | RPS6KA5METP2RX7RPS6KA4BRD4 | |
| SCHEMBL4870962 | 0.75 | P2RX7 (0.52) | RPS6KA5METP2RX7RPS6KA4CDC7 | |
| SCHEMBL14409583 | 0.74 | HTR2C (0.58) | RPS6KA5METP2RX7NR3C1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179066-A1 | ZWITTERIONIC ANTIBACTERIAL COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2025-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250179066-A1 | ZWITTERIONIC ANTIBACTERIAL COMPOUNDS | MRPL21, WIZ, CFTR | RPS6KA5 643/4885MET 4537/4885P2RX7 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.