Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | KRAS | P01116 | 5/20 | 0.36 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10064856 | 0.78 | GRM2 (0.42) | SLC6A4SLC6A2KRASHTR2AHTR7 | |
| SCHEMBL10064858 | 0.78 | GRM2 (0.42) | SLC6A4SLC6A2KRASHTR2AHTR7 | |
| SCHEMBL565845 | 0.78 | GRM2 (0.42) | SLC6A4SLC6A2KRASHTR2AHTR7 | |
| SCHEMBL18918053 | 0.77 | JAK1 (0.44) | — | |
| SCHEMBL18939739 | 0.76 | HTR7 (0.49) | SLC6A4SLC6A2HTR2AHTR7 | |
| SCHEMBL15205264 | 0.76 | ALDH1A1 (0.46) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL15205266 | 0.76 | ALDH1A1 (0.46) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL22439524 | 0.75 | HTR7 (0.48) | SLC6A4SLC6A2HTR2AHTR7 | |
| SCHEMBL30588239 | 0.75 | ALDH1A1 (0.38) | ALDH1A1HTTSMN1; SMN2SLC6A4SLC6A3 | |
| SCHEMBL31611505 | 0.75 | HTR7 (0.39) | SLC6A4SLC6A2KRASHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250177539-A1 | ER DEGRADERS AND USES THEREOF | ASTRAZENECA AB (SE) | 2025-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250177539-A1 | ER DEGRADERS AND USES THEREOF | ESR1, ESR2, ESRRA | ALDH1A1 1672/4885HTT 1084/4885SMN1; SMN2 455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.