Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.77 |
| ▸ | MEN1 | O00255 | 9/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.77 |
| ▸ | LMNA | P02545 | 5/20 | 0.77 |
| ▸ | HTT | P42858 | 3/20 | 0.77 |
| ▸ | NPC1 | O15118 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
| ▸ | PKM | P14618 | 1/20 | 0.77 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.77 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.72 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684597 | 1.00 | MAPT (0.77) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL31575065 | 0.90 | MEN1 (0.79) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL683772 | 0.90 | MEN1 (0.79) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL684889 | 0.90 | MAPT (0.77) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL19283322 | 0.89 | MEN1 (0.77) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL19283323 | 0.89 | MEN1 (0.77) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL15853618 | 0.89 | MEN1 (0.77) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL684936 | 0.87 | SIRT1 (0.67) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL13549794 | 0.87 | KMT2A (0.69) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL15887143 | 0.87 | KMT2A (1.00) | MAPTMEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101647-A9 | COMBINATION THERAPY OF ITRACONAZOLE AND ACYLHYDRAZONE-BASED ANTIFUNGALAGENTS FOR THE TREATMENT OF SPOROTRICHOSIS IN CATS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2025-06-12 | — | — | WO | disclosed |