Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.43 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20262009 | 0.88 | NPC1 (0.45) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL31616833 | 0.78 | MEN1 (0.59) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL375688 | 0.77 | LMNA (0.87) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL13135365 | 0.77 | NPC1 (0.65) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL28312216 | 0.76 | NPC1 (0.58) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL197322 | 0.75 | GRIK1 (0.53) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL197321 | 0.75 | GRIK1 (0.53) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10732288 | 0.75 | NPC1 (0.62) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL13135364 | 0.74 | LMNA (0.77) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL3975751 | 0.74 | P2RY4 (0.62) | NPC1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250189826-A1 | OPHTHALMIC DEVICES CONTAINING PHOTOSTABLE MIMICS OF MACULAR PIGMENT AND OTHER VISIBLE LIGHT FILTERS | JOHNSON & JOHNSON VISION CARE, INC. | 2025-06-12 | — | — | US | disclosed |