SCHEMBL375688

SCHEMBL375688

O=C1c2ccccc2C(=O)c2c(Nc3ccc(CCO)cc3)ccc(Nc3ccc(CCO)cc3)c21

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.87
MAPK1 P28482 3/20 0.87
NPC1 O15118 2/20 0.87
RAB9A P51151 2/20 0.87
MEN1 O00255 2/20 0.87
KMT2A Q03164 2/20 0.87
MAPT P10636 2/20 0.87
L3MBTL1 Q9Y468 2/20 0.87
NPSR1 Q6W5P4 1/20 0.87
TDP1 Q9NUW8 1/20 0.87
PRKCA P17252 2/20 0.54
SIRT2 Q8IXJ6 2/20 0.54
MTOR P42345 1/20 0.54
TOP2B Q02880 1/20 0.49
CYP1A2 P05177 2/20 0.47
TSHR P16473 1/20 0.47
CYP2C19 P33261 1/20 0.46
HIF1A Q16665 1/20 0.46
HSD17B10 Q99714 1/20 0.46
P2RY4 P51582 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13135364 0.93 LMNA (0.77) LMNAMAPK1NPC1RAB9AMEN1
SCHEMBL13370284 0.93 MEN1 (1.00) LMNAMAPK1NPC1RAB9AMEN1
SCHEMBL5553577 0.90 MAPT (0.72) LMNAMAPK1NPC1RAB9AMEN1
SCHEMBL8030800 0.89 LMNA (0.70) LMNAMAPK1NPC1RAB9AMEN1
SCHEMBL13909079 0.88 MAPT (0.69) LMNAMAPK1NPC1RAB9AMEN1
SCHEMBL14100826 0.88 LMNA (0.69) LMNAMAPK1NPC1RAB9AMEN1
SCHEMBL13135365 0.85 NPC1 (0.65) LMNAMAPK1NPC1RAB9AMEN1
SCHEMBL6067543 0.84 MAPT (0.64) LMNAMAPK1NPC1RAB9AMEN1
SCHEMBL11601873 0.84 MAPT (0.64) LMNAMAPK1NPC1RAB9AMEN1
SCHEMBL10732288 0.82 NPC1 (0.62) LMNAMAPK1NPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116574020-A Preparation and application of long-term stable silicone hydrogel contact lens colorant 华诺森(湖北)光学有限公司 2023-08-11 CN claimed
US-7504495-B2 Quencher compositions comprising anthraquinone moieties EXIQON A/S (DK) 2009-03-17 US claimed
EP-1538154-B1 Quencher composition comprising anthraquinone moieties EXIQON AS (DK) 2008-12-31 EP claimed
EP-1831394-A2 PROBES, LIBRARIES AND KITS FOR ANALYSIS OF MIXTURES OF NUCLEIC ACIDS AND METHODS FOR CONSTRUCTING THE SAME Exiqon A/S (DK) 2007-09-12 EP claimed
US-20060166238-A1 Probes, libraries and kits for analysis of mixtures of nucleic acids and methods for constructing the same EXIQON A/S (DK) 2006-07-27 US claimed
WO-2006066592-A2 PROBES, LIBRARIES AND KITS FOR ANALYSIS OF MIXTURES OF NUCLEIC ACIDS AND METHODS FOR CONSTRUCTING THE SAME EXIQON A/S (DK) 2006-06-29 WO claimed
US-20050227254-A1 Quencher compositions comprising anthraquinone moieties QIAGEN GMBH (DE) 2005-10-13 US claimed
EP-1538154-A1 Quencher composition comprising anthraquinone moieties Exiqon A/S (DK) 2005-06-08 EP claimed
WO-2024074814-A9 COMPOSITION COMPRISING A FUNCTIONALISED DYE AND A DIALLYLAMINE COMONOMER AND USE THEREOF SUBLINO LIMITED (GB) 2025-05-22 WO disclosed
US-20240209420-A1 COMPOSITIONS AND METHODS FOR MULTIPLEX DETECTION OF MIRNA AND OTHER POLYNUCELOTIDES KASA BIO, L.L.C. 2024-06-27 US disclosed
EP-4388133-A2 COMPOSITIONS AND METHODS FOR MULTIPLEX DETECTION OF MIRNA AND OTHER POLYNUCELOTIDES Kasa Bio, L.L.C. (US) 2024-06-26 EP disclosed
US-11952617-B2 Methods for multiplex detection of polynucleotides using unbound fluorescent probes and quencher oligonucleotides KASA BIO, L.L.C. (US) 2024-04-09 US disclosed
US-20230265490-A1 COMPOSITIONS AND METHODS FOR MULTIPLEX DETECTION OF MIRNA AND OTHER POLYNUCLEOTIDES KASA BIO, L.L.C. 2023-08-24 US disclosed
CN-116574020-A Preparation and application of long-term stable silicone hydrogel contact lens colorant 华诺森(湖北)光学有限公司 2023-08-11 CN disclosed
WO-2005098029-A2 METHODS FOR QUANTIFICATION OF MICRORNAS AND SMALL INTERFERING RNAS EXIQON A/S (DK) 2005-10-20 WO disclosed
US-20050227254-A1 Quencher compositions comprising anthraquinone moieties QIAGEN GMBH (DE) 2005-10-13 US disclosed
EP-1538154-A1 Quencher composition comprising anthraquinone moieties Exiqon A/S (DK) 2005-06-08 EP disclosed
EP-0555361-B1 POWDER COLORANT COMPOSITIONS AND PROCESS FOR THE PREPARATION THEREOF EASTMAN CHEM CO (US) 1995-01-11 EP disclosed
EP-0555361-A1 POWDER COLORANT COMPOSITIONS AND PROCESS FOR THE PREPARATION THEREOF. EASTMAN KODAK CO (US) 1993-08-18 EP disclosed
WO-1992007913-A1 POWDER COLORANT COMPOSITIONS AND PROCESS FOR THE PREPARATION THEREOF EASTMAN KODAK COMPANY (US) 1992-05-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050227254-A1 Quencher compositions comprising anthraquinone moieties ANXA5, SUN2, ANXA3 LMNA 522/4885MAPK1 2569/4885NPC1 4101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.