Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720275 | 1.00 | CCR8 (0.41) | CCR8KMT2AATMGFER | |
| SCHEMBL3936163 | 0.88 | CCR8 (0.39) | CCR8KMT2AATMGFER | |
| SCHEMBL4719742 | 0.88 | CCR8 (0.39) | CCR8KMT2AATMGFER | |
| SCHEMBL4718978 | 0.87 | CCR8 (0.54) | CCR8KMT2AATM | |
| SCHEMBL4716229 | 0.87 | CCR8 (0.42) | CCR8 | |
| SCHEMBL4718843 | 0.83 | CCR8 (0.42) | CCR8KMT2AATMGFER | |
| SCHEMBL4716876 | 0.83 | PKM (0.45) | CCR8 | |
| SCHEMBL3918455 | 0.81 | CCR8 (0.49) | CCR8 | |
| SCHEMBL4720019 | 0.81 | CCR8 (0.53) | CCR8KMT2A | |
| SCHEMBL3161685 | 0.79 | KMT2A (0.41) | KMT2AATMGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567520-B1 | QUINOLINES AND NITROGENATED DERIVATIVES THEREOF AND THEIR USE AS ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2008-10-15 | — | — | EP | claimed |