Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.30 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31612758 | 0.83 | BRD9 (0.40) | GRIN1GRIN2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL31617117 | 0.80 | AURKA (0.36) | AURKASYKAURKBCNR1LMNA | |
| SCHEMBL31612727 | 0.74 | COMT (0.37) | LMNAHTTSMN1; SMN2MAPTNPSR1 | |
| SCHEMBL31612726 | 0.74 | COMT (0.37) | LMNAHTTSMN1; SMN2MAPTNPSR1 | |
| SCHEMBL25219333 | 0.73 | DGAT1 (0.39) | GRIN1GRIN2AAR | |
| SCHEMBL24739013 | 0.73 | NPBWR1 (0.52) | AURKAAURKBMAPT | |
| SCHEMBL31612718 | 0.69 | BRD4 (0.36) | ARNOTUM | |
| SCHEMBL4223674 | 0.67 | CNR1 (0.33) | AURKASYKAURKBCNR1ALDH1A1 | |
| SCHEMBL31617113 | 0.66 | AURKA (0.41) | AURKASYKAURKBCNR1LMNA | |
| SCHEMBL25305648 | 0.64 | AKR1C3 (0.38) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025119372-A2 | MRGPRX2 ANTAGONIST AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2025-06-12 | — | — | WO | disclosed |