Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | MAT2A | P31153 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | RORA | P35398 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17610151 | 0.72 | KDM4C (0.45) | PLK1MAT2ACNR1KDM4CRORC | |
| Hydrochloric Acid SCHEMBL31617122 | 0.71 | AURKA (0.38) | AURKASYKAURKBCNR1METAP2 | |
| SCHEMBL23993327 | 0.69 | ESR1 (0.44) | KDM4CRORCMETAP2ESR1 | |
| SCHEMBL17610149 | 0.69 | KDM4C (0.38) | MAT2ACNR1KDM4CALDH1A1LMNA | |
| SCHEMBL21204911 | 0.69 | KMO (0.57) | MAT2AKDM4CESR1MAPK8 | |
| SCHEMBL20820754 | 0.69 | KDM4C (0.38) | MAT2AKDM4CMEN1KMT2ALMNA | |
| SCHEMBL23994521 | 0.67 | HTR3A (0.42) | AURKASYKAURKBCNR1CYP1A2 | |
| SCHEMBL31617117 | 0.66 | AURKA (0.36) | AURKASYKAURKBCNR1ALDH1A1 | |
| SCHEMBL31617121 | 0.66 | AURKA (0.36) | AURKASYKAURKBCNR1ALDH1A1 | |
| SCHEMBL22064905 | 0.65 | ALDH1A1 (0.69) | MEN1KMT2AALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025119372-A2 | MRGPRX2 ANTAGONIST AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2025-06-12 | — | — | WO | disclosed |