Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 2/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.49 |
| ▸ | GABRP | O00591 | 1/20 | 0.49 |
| ▸ | GABRD | O14764 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.49 |
| ▸ | GABRE | P78334 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380449 | 0.83 | CNR2 (0.55) | GABRG2GABRB3GABRA5GABRPGABRD | |
| SCHEMBL2216224 | 0.82 | KDM4E (0.59) | GABRG2GABRB3GABRA5GABRPGABRD | |
| SCHEMBL27939713 | 0.82 | KMT2A (0.46) | GABRG2GABRB3GABRA5GABRPGABRD | |
| SCHEMBL27962863 | 0.82 | GABRG2 (0.61) | GABRG2GABRB3GABRA5GABRPGABRD | |
| SCHEMBL2215683 | 0.80 | CYP19A1 (0.57) | GABRG2GABRB3GABRA5GABRPGABRD | |
| SCHEMBL31623753 | 0.80 | CNR2 (0.52) | GABRG2GABRB3GABRA5GABRPGABRD | |
| SCHEMBL5096226 | 0.78 | NPY5R (0.47) | GABRG2GABRB3GABRA5GABRPGABRD | |
| SCHEMBL2212614 | 0.78 | CNR2 (0.56) | KMT2APOLBCNR2KDM4EALDH1A1 | |
| SCHEMBL8593647 | 0.78 | GABRP (0.43) | GABRG2GABRB3GABRA5GABRPGABRD | |
| SCHEMBL30344008 | 0.78 | POLB (0.64) | KMT2APOLBKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025128933-A1 | GABA-A RECEPTOR POSITIVE ALLOSTERIC MODULATORS AND METHODS OF USE THEREOF | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2025-06-19 | — | — | WO | disclosed |