Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.39 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 8/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 7/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 6/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 3/20 | 0.32 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316245 | 1.00 | MKNK1 (0.39) | MKNK1MKNK2INPPL1CYP11B2DYRK1A | |
| SCHEMBL2412655 | 0.85 | IRAK1 (0.42) | FGFR3FGFR2FGFR4PDK2IRAK1 | |
| SCHEMBL2412658 | 0.85 | IRAK1 (0.42) | FGFR3FGFR2FGFR4PDK2IRAK1 | |
| SCHEMBL315031 | 0.84 | CYP1A1 (0.41) | MKNK1MKNK2CYP11B2 | |
| SCHEMBL315032 | 0.84 | CYP1A1 (0.41) | MKNK1MKNK2CYP11B2 | |
| SCHEMBL314720 | 0.83 | CYP2A6 (0.35) | CYP11B2 | |
| SCHEMBL314721 | 0.83 | CYP2A6 (0.35) | CYP11B2 | |
| SCHEMBL314972 | 0.83 | CHRNB1 (0.36) | — | |
| SCHEMBL314973 | 0.83 | CHRNB1 (0.36) | — | |
| SCHEMBL2142244 | 0.81 | CHRNB1 (0.41) | MKNK1MKNK2CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093394-B2 | Derivatives of 5-thioxylopyranose and use of same for treatment | LABORATOIRES FOURNIER S.A. (FR) | 2012-01-10 | — | — | US | disclosed |
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |
| US-20090182013-A1 | Derivatives of 5-Thioxylopyranose and Use of Same for Treatment | LABORATOIRES FOURNIER S.A. (FR) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182013-A1 | Derivatives of 5-Thioxylopyranose and Use of Same for Treatment | TPMT, PNPO, PPOX | MKNK1 3785/4885MKNK2 3726/4885INPPL1 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.