Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31629158 | 0.90 | F2RL1 (0.35) | DGAT1KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31629443 | 0.89 | DGAT1 (0.37) | DGAT1KCNH2 | |
| SCHEMBL31629432 | 0.86 | DGAT1 (0.33) | DGAT1KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31629440 | 0.84 | DGAT1 (0.36) | DGAT1F2RL1 | |
| SCHEMBL31629429 | 0.82 | DGAT1 (0.31) | DGAT1F2RL1 | |
| SCHEMBL31629065 | 0.80 | SLC6A2 (0.31) | DGAT1SLC6A2SLC6A4SLC6A3F2RL1 | |
| SCHEMBL31628934 | 0.79 | F2RL1 (0.33) | DGAT1KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31631795 | 0.78 | F2RL1 (0.35) | DGAT1KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31629117 | 0.78 | SLC6A2 (0.30) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31629326 | 0.78 | GABRP (0.31) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025125666-A1 | SUBSTITUTED IMIDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-06-19 | — | — | WO | disclosed |