Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31629110 | 0.84 | DGAT1 (0.33) | DGAT1F2RL1 | |
| SCHEMBL31629432 | 0.82 | DGAT1 (0.33) | DGAT1F2RL1 | |
| SCHEMBL31628946 | 0.82 | ALDH1A1 (0.38) | DGAT1ALDH1A1F2RL1MEN1MAPT | |
| SCHEMBL31629429 | 0.81 | DGAT1 (0.31) | DGAT1F2RL1 | |
| SCHEMBL31629099 | 0.81 | GRIN2B (0.38) | ALDH1A1F2RL1MEN1MAPTCASP3 | |
| SCHEMBL31631795 | 0.77 | F2RL1 (0.35) | DGAT1F2RL1GRIN1GRIN2B | |
| SCHEMBL13734459 | 0.77 | DGAT1 (0.41) | DGAT1F2RL1MAPTF11 | |
| SCHEMBL31629158 | 0.77 | F2RL1 (0.35) | DGAT1F2RL1 | |
| SCHEMBL31628951 | 0.76 | MAPK1 (0.33) | DGAT1F2RL1F11MAPK1GRIN1 | |
| SCHEMBL13734768 | 0.76 | DGAT1 (0.40) | DGAT1F2RL1MAPTF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025125666-A1 | SUBSTITUTED IMIDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-06-19 | — | — | WO | disclosed |