Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31631819 | 0.87 | DGAT1 (0.32) | DGAT1NPC1 | |
| SCHEMBL1396117 | 0.78 | DGAT1 (0.37) | DGAT1NPC1ALOX5APFEN1 | |
| SCHEMBL2822834 | 0.76 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL22093263 | 0.76 | CPB1 (0.33) | DGAT1NPC1 | |
| SCHEMBL29218325 | 0.75 | NPC1 (0.40) | DGAT1NPC1 | |
| SCHEMBL111672 | 0.75 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL31091884 | 0.75 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL19924651 | 0.75 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL2147273 | 0.75 | DGAT1 (0.42) | DGAT1 | |
| SCHEMBL25213344 | 0.75 | TBXAS1 (0.34) | NPC1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025125665-A1 | FURTHER SUBSTITUTED IMIDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-06-19 | — | — | WO | disclosed |