Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23122092 | 0.75 | HSD17B10 (0.55) | ALDH1A1HSD17B10TDP1PARP1PRKCI | |
| SCHEMBL16728898 | 0.74 | RAB9A (0.52) | ALDH1A1RAB9AL3MBTL1KDM4ECYP1A2 | |
| SCHEMBL22042885 | 0.74 | ALDH1A1 (0.51) | ALDH1A1HSD17B10RAB9AGSK3BL3MBTL1 | |
| SCHEMBL10429315 | 0.73 | ALDH1A1 (0.50) | ALDH1A1HSD17B10RAB9AL3MBTL1KDM4E | |
| SCHEMBL13787655 | 0.70 | ALDH1A1 (0.43) | ALDH1A1HSD17B10TDP1PARP1PRKCI | |
| SCHEMBL23122788 | 0.69 | RAB9A (0.50) | ALDH1A1RAB9AL3MBTL1KDM4ECA9 | |
| SCHEMBL7480357 | 0.68 | ALDH1A1 (0.45) | ALDH1A1HSD17B10TDP1PARP1PRKCI | |
| SCHEMBL2644551 | 0.68 | RAB9A (0.49) | ALDH1A1HSD17B10RAB9AL3MBTL1CA9 | |
| SCHEMBL6035072 | 0.68 | RAB9A (0.49) | ALDH1A1HSD17B10RAB9AL3MBTL1CA9 | |
| SCHEMBL23121848 | 0.67 | ALDH1A1 (0.37) | ALDH1A1HSD17B10TDP1PARP1PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025129167-A1 | INHIBITORS OF THE SURFACE EXPRESSION OF THE VOLTAGE-GATED SODIUM ION CHANNEL 1.7 (NAV1.7) AND THEIR THERAPEUTIC USES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2025-06-19 | — | — | WO | disclosed |