Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 11/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418912 | 0.87 | SPR (0.72) | SPRHPGDLMNAL3MBTL1NR3C1 | |
| SCHEMBL31632806 | 0.81 | PLK1 (0.47) | SPRLMNAL3MBTL1MAPTPLK1 | |
| SCHEMBL31632800 | 0.79 | SCN2B (0.49) | SPRL3MBTL1ALDH1A1 | |
| SCHEMBL21500663 | 0.78 | SPR (0.69) | SPRHPGDLMNAL3MBTL1NR3C1 | |
| SCHEMBL5070874 | 0.72 | SPR (0.61) | SPRHPGDLMNAL3MBTL1NR3C1 | |
| SCHEMBL13202016 | 0.72 | HPGD (0.53) | HPGDMAPTMAPK1 | |
| SCHEMBL31633080 | 0.72 | HPGD (0.53) | HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL20551408 | 0.71 | HPGD (0.54) | HPGDL3MBTL1MAPTCFTR | |
| SCHEMBL31633025 | 0.71 | KMT2A (0.47) | HPGDL3MBTL1MAPTKDM4EALDH1A1 | |
| SCHEMBL24051741 | 0.70 | ALKBH1 (0.40) | SPRHPGDLMNAL3MBTL1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025129167-A1 | INHIBITORS OF THE SURFACE EXPRESSION OF THE VOLTAGE-GATED SODIUM ION CHANNEL 1.7 (NAV1.7) AND THEIR THERAPEUTIC USES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2025-06-19 | — | — | WO | disclosed |