Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2B | O60939 | 3/20 | 0.49 |
| ▸ | SCN1B | Q07699 | 3/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.49 |
| ▸ | SCN1A | P35498 | 2/20 | 0.49 |
| ▸ | SPR | P35270 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6840243 | 0.79 | SCN2B (0.70) | SCN2BSCN1BSCN5ASCN9ASCN1A | |
| SCHEMBL31633159 | 0.79 | SPR (0.64) | SPRALDH1A1L3MBTL1 | |
| SCHEMBL31633080 | 0.77 | HPGD (0.53) | KMT2ANOTUMALDH1A1L3MBTL1MAPK14 | |
| SCHEMBL13202016 | 0.77 | HPGD (0.53) | KMT2AMAPK14 | |
| SCHEMBL17963082 | 0.72 | HCAR2 (0.40) | SPRPTPN11ALDH1A1L3MBTL1RXRA | |
| SCHEMBL25588028 | 0.71 | HCAR2 (0.39) | SPRKMT2APTPN11ALDH1A1RXRA | |
| SCHEMBL31403687 | 0.70 | HCAR3 (0.41) | PTPN11RXRA | |
| SCHEMBL31403685 | 0.70 | HCAR3 (0.41) | PTPN11RXRA | |
| SCHEMBL28770755 | 0.68 | NOTUM (0.49) | SPRKMT2ANOTUMALDH1A1L3MBTL1 | |
| SCHEMBL20318948 | 0.68 | HCAR2 (0.36) | SPRPTPN11ALDH1A1CYP1A2RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025129167-A1 | INHIBITORS OF THE SURFACE EXPRESSION OF THE VOLTAGE-GATED SODIUM ION CHANNEL 1.7 (NAV1.7) AND THEIR THERAPEUTIC USES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2025-06-19 | — | — | WO | disclosed |