Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.65 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.65 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30505727 | 0.80 | ALDH1A1 (0.55) | KEAP1NFE2L2GLO1PTGS1PTGS2 | |
| SCHEMBL31562182 | 0.80 | KEAP1 (0.49) | KEAP1NFE2L2GLO1L3MBTL1NR3C1 | |
| SCHEMBL15108064 | 0.79 | KEAP1 (1.00) | KEAP1NFE2L2GLO1PTGS1PTGS2 | |
| SCHEMBL28299609 | 0.79 | KEAP1 (0.41) | KEAP1NFE2L2L3MBTL1HTTALDH1A1 | |
| SCHEMBL1476351 | 0.78 | KEAP1 (0.70) | KEAP1NFE2L2GLO1PTGS1PTGS2 | |
| SCHEMBL11516751 | 0.76 | KEAP1 (0.68) | KEAP1NFE2L2GLO1PTGS1PTGS2 | |
| SCHEMBL1290987 | 0.76 | KEAP1 (0.67) | KEAP1NFE2L2GLO1PTGS1PTGS2 | |
| SCHEMBL9686322 | 0.76 | KEAP1 (0.67) | KEAP1NFE2L2GLO1PTGS1PTGS2 | |
| SCHEMBL66979 | 0.75 | ALDH1A1 (0.52) | KEAP1NFE2L2ALDH1A1KMT2AKDM4E | |
| SCHEMBL2009844 | 0.74 | KEAP1 (0.38) | KEAP1NFE2L2ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116675635-B | Method for synthesizing 3-vinyl indole-2-ketone derivative with high stereoselectivity | 常州大学 | 2025-06-24 | — | — | CN | disclosed |