Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4844424 | 0.86 | PARP1 (0.46) | ALDH1A1MAPTSMN1; SMN2PARP1KMT2A | |
| SCHEMBL4844436 | 0.86 | PARP1 (0.46) | ALDH1A1MAPTSMN1; SMN2PARP1KMT2A | |
| SCHEMBL8116046 | 0.81 | CHEK2 (0.44) | ALDH1A1KDM4EMAPTSMN1; SMN2PARP1 | |
| SCHEMBL30165832 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1MAPTLMNA | |
| SCHEMBL6184282 | 0.79 | CHRNB4 (0.48) | ALDH1A1KDM4ETDP1MAPTLMNA | |
| SCHEMBL6191591 | 0.79 | CHRNB4 (0.48) | ALDH1A1KDM4ETDP1MAPTLMNA | |
| SCHEMBL31218714 | 0.78 | KDM4E (0.45) | ALDH1A1KDM4EMAPTLMNAPARP1 | |
| SCHEMBL8391746 | 0.76 | PARP1 (0.50) | ALDH1A1SMN1; SMN2PARP1 | |
| SCHEMBL8391745 | 0.76 | PARP1 (0.50) | ALDH1A1SMN1; SMN2PARP1 | |
| SCHEMBL30032878 | 0.76 | MAPT (0.47) | ALDH1A1KDM4ETDP1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120202200-A | Oxo-isoindolinyl substituted tetrahydropyrimidinedione-based compounds and applications thereof | 标新生物医药科技(上海)有限公司 | 2025-06-24 | — | — | CN | disclosed |