SCHEMBL31637720

SCHEMBL31637720

CC(=O)NC12CC(C(F)(F)C(F)(F)F)(C1)C2

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21064405 0.83 ALDH1A1 (0.33) ALDH1A1KDM4EGAAMAPTHTT
SCHEMBL16118625 0.77
SCHEMBL17586261 0.75 HPGDS (0.37) HTT
SCHEMBL11224012 0.75 KDM4E (0.37) ALDH1A1KDM4EGAA
SCHEMBL16118629 0.75 KDM4E (0.37) ALDH1A1KDM4EGAA
SCHEMBL25857001 0.72 EPHX2 (0.45) KDM4E
SCHEMBL31493470 0.71
SCHEMBL31493481 0.71
SCHEMBL31637665 0.69 ALDH1A1 (0.36) ALDH1A1KDM4EGAAMAPTHTT
SCHEMBL16039566 0.69 EPHX1 (0.32) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025137599-A1 WRN INHIBITORS NIMBUS WADJET, INC. (US) 2025-06-26 WO disclosed