Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639399 | 0.79 | CDK2 (0.37) | — | |
| SCHEMBL31639315 | 0.79 | POLB (0.31) | POLB | |
| SCHEMBL31639212 | 0.75 | TRPV3 (0.42) | TRPV3POLB | |
| SCHEMBL31639581 | 0.75 | TNF (0.37) | POLB | |
| SCHEMBL31639441 | 0.75 | SMPD3 (0.34) | POLB | |
| SCHEMBL31639603 | 0.72 | DHODH (0.35) | POLB | |
| SCHEMBL31639175 | 0.69 | NRAS (0.36) | PDE4D | |
| SCHEMBL30698331 | 0.67 | NRAS (0.40) | PDE4D | |
| SCHEMBL31739608 | 0.67 | NRAS (0.40) | PDE4D | |
| SCHEMBL30698334 | 0.66 | KDM4E (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137567-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-06-26 | — | — | WO | disclosed |