Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639441 | 0.85 | SMPD3 (0.34) | POLBTP53HPGDPDE2A | |
| SCHEMBL31639315 | 0.81 | POLB (0.31) | POLB | |
| SCHEMBL31639603 | 0.79 | DHODH (0.35) | POLBTP53HPGD | |
| SCHEMBL31639364 | 0.79 | TNF (0.32) | TNF | |
| SCHEMBL31639293 | 0.76 | TRPV3 (0.37) | TP53HPGD | |
| SCHEMBL31639308 | 0.75 | TRPV3 (0.31) | POLB | |
| SCHEMBL30698345 | 0.72 | FYN (0.40) | TNF | |
| SCHEMBL31639345 | 0.65 | FYN (0.36) | — | |
| SCHEMBL31639289 | 0.64 | KDM4E (0.36) | HPGDPDE10A | |
| SCHEMBL31639512 | 0.63 | PDE4D (0.33) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137567-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-06-26 | — | — | WO | disclosed |