⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639473 | 0.82 | — | — | |
| SCHEMBL30698334 | 0.75 | KDM4E (0.32) | — | |
| SCHEMBL31000272 | 0.68 | PDE4B (0.34) | — | |
| SCHEMBL31000313 | 0.68 | SUV39H2 (0.33) | — | |
| SCHEMBL31639341 | 0.67 | PDE10A (0.34) | — | |
| SCHEMBL31639512 | 0.67 | PDE4D (0.33) | — | |
| SCHEMBL31000296 | 0.65 | PDE4B (0.36) | — | |
| SCHEMBL31639289 | 0.65 | KDM4E (0.36) | — | |
| SCHEMBL31639231 | 0.64 | HPGD (0.34) | — | |
| SCHEMBL31639301 | 0.63 | KDM4E (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137567-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-06-26 | — | — | WO | disclosed |