Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GRN | P28799 | 1/20 | 0.31 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31647289 | 0.82 | NMT1 (0.37) | KMT2ANMT1MCL1MAPK8KDM4E | |
| SCHEMBL20356427 | 0.82 | L3MBTL1 (0.30) | L3MBTL1 | |
| SCHEMBL13106248 | 0.77 | ADORA2A (0.42) | L3MBTL1NMT1LMNAMAPK8KDM4E | |
| SCHEMBL20520461 | 0.76 | PDK1 (0.36) | L3MBTL1KMT2ANMT1MCL1EGLN1 | |
| SCHEMBL20356426 | 0.74 | L3MBTL1 (0.33) | L3MBTL1NMT1MAPK8 | |
| SCHEMBL1965759 | 0.72 | ELANE (0.48) | MCL1MAPK8KDM4E | |
| SCHEMBL13106358 | 0.72 | GAA (0.32) | NMT1MAPK8 | |
| SCHEMBL21226504 | 0.71 | PDK1 (0.42) | KMT2ALMNAKDM4EGRNSORT1 | |
| SCHEMBL4040813 | 0.71 | HSD17B10 (0.41) | KMT2AKDM4EGRNSORT1 | |
| SCHEMBL30976257 | 0.70 | ALDH1A1 (0.44) | L3MBTL1KMT2ALMNAMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025133961-A1 | NITROGEN-CONTAINING HETEROARYL COMPOUNDS FOR THE TREATMENT OF CHRONIC DISEASES | PFIZER INC. (US) | 2025-06-26 | — | — | WO | disclosed |