SCHEMBL31647697

SCHEMBL31647697

N#Cc1cc2c(nc1Cl)CCN(Cc1ccccc1)C2

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.60
MEN1 O00255 2/20 0.60
NPC1 O15118 1/20 0.60
RAB9A P51151 1/20 0.60
KDM4E B2RXH2 2/20 0.57
ALDH1A1 P00352 2/20 0.57
HPGD P15428 2/20 0.57
GLA P06280 1/20 0.57
GAA P10253 1/20 0.57
MAPT P10636 1/20 0.57
DHFR P00374 1/20 0.54
ACHE P22303 5/20 0.52
SMN1; SMN2 Q16637 1/20 0.50
BCHE P06276 3/20 0.48
C5AR1 P21730 1/20 0.47
HIF1A Q16665 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
PNMT P11086 1/20 0.45
ADORA1 P30542 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8567861 0.87 DHFR (0.61) KMT2AMEN1NPC1RAB9AKDM4E
SCHEMBL17985055 0.83 KMT2A (0.67) KMT2AMEN1NPC1RAB9AKDM4E
SCHEMBL18550404 0.81 KMT2A (0.64) KMT2AMEN1NPC1RAB9AKDM4E
SCHEMBL31647528 0.80 MEN1 (0.51) KMT2AMEN1NPC1RAB9AKDM4E
SCHEMBL5775069 0.79 KMT2A (0.57) KMT2AMEN1NPC1RAB9AKDM4E
SCHEMBL31647626 0.76 ALDH1A1 (0.67) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL1036093 0.76 SMN1; SMN2 (0.60) KMT2AMEN1RAB9AKDM4EALDH1A1
SCHEMBL23151747 0.76 ALDH1A1 (0.70) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL29620560 0.76 ALDH1A1 (0.70) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL6606580 0.76 MEN1 (1.00) KMT2AMEN1NPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025134078-A1 ORGANIC COMPOUNDS AS MUSCARINIC M4 RECEPTOR POSITIVE ALLOSTERIC MODULATORS (M4 PAMS) SUVEN LIFE SCIENCES LIMITED (IN) 2025-06-26 WO disclosed