Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.38 |
| ▸ | BTK | Q06187 | 3/20 | 0.38 |
| ▸ | LPL | P06858 | 3/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263386 | 0.86 | LPL (0.39) | LPLLIPGTNFNR1I2LIPE | |
| SCHEMBL29574549 | 0.86 | LPL (0.39) | LPLLIPGTNFNR1I2LIPE | |
| SCHEMBL2026497 | 0.85 | LPL (0.38) | JAK2BTKLPLLIPGTNF | |
| SCHEMBL26197525 | 0.82 | LPL (0.33) | JAK2BTKLPLLIPGTNF | |
| SCHEMBL1870652 | 0.81 | JAK2 (0.38) | JAK2BTKLPLLIPG | |
| SCHEMBL26187067 | 0.79 | LIPE (0.38) | JAK2BTKLPLLIPGLIPE | |
| SCHEMBL4315605 | 0.78 | KMT2A (0.35) | LPLLIPGTNFLIPE | |
| SCHEMBL11927624 | 0.78 | LPL (0.44) | JAK2BTKLPLLIPGP2RX7 | |
| SCHEMBL20836424 | 0.78 | JAK2 (0.35) | JAK2BTKLPLLIPG | |
| SCHEMBL30594525 | 0.78 | JAK2 (0.35) | JAK2BTKLPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132946-A1 | PHENYLPYRROLIDINE DERIVATIVES AND THEIR USE AS POI-THETA DERIVATIVES | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |