Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31648045 | 0.92 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1GAAPOLQMAPT | |
| SCHEMBL31648052 | 0.90 | PPIB (0.39) | HSP90AA1HSP90AB1 | |
| SCHEMBL31648538 | 0.85 | PPIB (0.40) | HSP90AA1HSP90AB1GRM5 | |
| SCHEMBL31648466 | 0.85 | PPIB (0.40) | HSP90AA1HSP90AB1GRM5 | |
| SCHEMBL31648823 | 0.85 | PPIB (0.38) | HSP90AA1HSP90AB1GRM5GPBAR1 | |
| SCHEMBL31648798 | 0.85 | MEN1 (0.39) | HSP90AA1HSP90AB1GAAMAPTTP53 | |
| SCHEMBL31648942 | 0.85 | MEN1 (0.39) | HSP90AA1HSP90AB1GAAMAPTTP53 | |
| SCHEMBL31648507 | 0.79 | SIGMAR1 (0.37) | HSP90AA1HSP90AB1SMN1; SMN2 | |
| SCHEMBL31648206 | 0.76 | GAA (0.42) | HSP90AA1HSP90AB1GAATSHRGRM5 | |
| SCHEMBL31648311 | 0.73 | ALDH1A1 (0.44) | GAAPOLQTP53SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132946-A1 | PHENYLPYRROLIDINE DERIVATIVES AND THEIR USE AS POI-THETA DERIVATIVES | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | claimed |
| WO-2025132946-A1 | PHENYLPYRROLIDINE DERIVATIVES AND THEIR USE AS POI-THETA DERIVATIVES | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |