Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.39 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31648942 | 1.00 | MEN1 (0.39) | MEN1KMT2AYAP1TEAD4KDM4E | |
| SCHEMBL31648045 | 0.88 | HSP90AA1 (0.44) | MEN1KMT2AGAAALDH1A1TP53 | |
| SCHEMBL31648577 | 0.85 | HSP90AA1 (0.36) | MEN1KMT2AGAATP53MAPT | |
| SCHEMBL31648052 | 0.81 | PPIB (0.39) | ALOX15HSP90AA1HSP90AB1 | |
| SCHEMBL31648823 | 0.79 | PPIB (0.38) | HSP90AA1HSP90AB1 | |
| SCHEMBL31648466 | 0.76 | PPIB (0.40) | ALOX15HSP90AA1HSP90AB1 | |
| SCHEMBL31648538 | 0.76 | PPIB (0.40) | ALOX15HSP90AA1HSP90AB1 | |
| SCHEMBL31648311 | 0.73 | ALDH1A1 (0.44) | KMT2AGAAALDH1A1TP53LMNA | |
| Lithium Ion SCHEMBL31648320 | 0.71 | POLQ (0.35) | — | |
| SCHEMBL31648183 | 0.69 | ALDH1A1 (0.41) | MEN1KMT2AKDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132946-A1 | PHENYLPYRROLIDINE DERIVATIVES AND THEIR USE AS POI-THETA DERIVATIVES | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |