Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31648183 | 0.92 | ALDH1A1 (0.41) | MAPK1LMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL31648679 | 0.84 | POLQ (0.43) | MAPK1KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL31648531 | 0.83 | ALDH1A1 (0.46) | LMNAKMT2AALDH1A1TSHRGAA | |
| SCHEMBL31648567 | 0.78 | MAPK1 (0.41) | MAPK1LMNAKMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL31648774 | 0.76 | POLQ (0.38) | MAPK1LMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL31648311 | 0.75 | ALDH1A1 (0.44) | LMNAKMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL15724348 | 0.75 | MAPK1 (0.40) | MAPK1LMNAKMT2AKDM4EALDH1A1 | |
| Lithium Ion SCHEMBL31648320 | 0.73 | POLQ (0.35) | — | |
| SCHEMBL14488238 | 0.71 | MAPK1 (0.40) | MAPK1LMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL20756450 | 0.71 | TRPM2 (0.41) | MAPK1LMNAKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132946-A1 | PHENYLPYRROLIDINE DERIVATIVES AND THEIR USE AS POI-THETA DERIVATIVES | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |