Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649412 | 0.86 | KMT2A (0.43) | ALDH1A1KDM4EMAPK1HTTKMT2A | |
| SCHEMBL31649370 | 0.86 | KMT2A (0.43) | ALDH1A1KDM4EMAPK1HTTKMT2A | |
| SCHEMBL31649235 | 0.85 | HTR2A (0.41) | ALDH1A1L3MBTL1HTTKMT2AMEN1 | |
| SCHEMBL31649298 | 0.81 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4EHPGDL3MBTL1 | |
| SCHEMBL31649339 | 0.81 | DPP4 (0.42) | ALDH1A1HPGD | |
| SCHEMBL31649393 | 0.79 | TSHR (0.41) | ALDH1A1MAPTKDM4EMAPK1HTT | |
| SCHEMBL31649406 | 0.78 | KMT2A (0.40) | ALDH1A1KDM4EMAPK1HTTKMT2A | |
| SCHEMBL31649053 | 0.78 | KMT2A (0.40) | ALDH1A1KDM4EMAPK1HTTKMT2A | |
| SCHEMBL31649260 | 0.77 | HTR2A (0.41) | ALDH1A1L3MBTL1HTTKMT2AMEN1 | |
| SCHEMBL31649325 | 0.77 | KMT2A (0.40) | ALDH1A1KDM4EMAPK1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | claimed |
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |