Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649410 | 0.86 | KMT2A (0.45) | KMT2AMEN1DPP7TACR1TSHR | |
| SCHEMBL31649178 | 0.86 | KMT2A (0.45) | KMT2AMEN1DPP7TACR1TSHR | |
| SCHEMBL31649329 | 0.82 | KMT2A (0.41) | KMT2AMEN1DPP7TACR1TSHR | |
| SCHEMBL31649366 | 0.82 | F2 (0.45) | KMT2AMEN1DPP7TACR1TSHR | |
| SCHEMBL31649086 | 0.81 | F2 (0.44) | KMT2AMEN1DPP7TACR1TSHR | |
| SCHEMBL31649148 | 0.81 | KMT2A (0.41) | KMT2AMEN1DPP7TACR1TSHR | |
| SCHEMBL31649427 | 0.81 | ALDH1A1 (0.46) | KMT2AMEN1TACR1TSHRLMNA | |
| SCHEMBL31649149 | 0.80 | KMT2A (0.39) | KMT2AMEN1DPP7TSHRMAPK1 | |
| SCHEMBL31649068 | 0.80 | F2 (0.43) | KMT2AMEN1DPP7TACR1LMNA | |
| SCHEMBL31649352 | 0.79 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |