Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | TRHR | P34981 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PDE9A | O76083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649270 | 0.83 | DPP7 (0.39) | KMT2AMEN1DPP7DPP4TSHR | |
| SCHEMBL31649410 | 0.81 | KMT2A (0.45) | KMT2AMEN1DPP7TACR1TSHR | |
| SCHEMBL31649178 | 0.81 | KMT2A (0.45) | KMT2AMEN1DPP7TACR1TSHR | |
| SCHEMBL31649428 | 0.81 | KMT2A (0.45) | KMT2AMEN1DPP7DPP4TACR1 | |
| SCHEMBL31649329 | 0.77 | KMT2A (0.41) | KMT2AMEN1DPP7TACR1TSHR | |
| SCHEMBL31649366 | 0.77 | F2 (0.45) | KMT2AMEN1DPP7TACR1TSHR | |
| SCHEMBL31649086 | 0.76 | F2 (0.44) | KMT2AMEN1DPP7TACR1TSHR | |
| SCHEMBL31649427 | 0.76 | ALDH1A1 (0.46) | KMT2AMEN1TACR1TSHR | |
| SCHEMBL31649328 | 0.76 | TACR1 (0.42) | KMT2AMEN1DPP7TACR1TSHR | |
| SCHEMBL31649352 | 0.74 | ALDH1A1 (0.43) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |