Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CPS1 | P31327 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649382 | 0.85 | KMT2A (0.38) | ALDH1A1ADRB2MEN1KMT2ACPS1 | |
| SCHEMBL31649458 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KMT2AHSD11B1EPHX2 | |
| SCHEMBL31649113 | 0.84 | TACR1 (0.39) | ALDH1A1MEN1KMT2APOLBKDM1A | |
| SCHEMBL31649298 | 0.84 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2APOLBHTT | |
| SCHEMBL31649410 | 0.80 | KMT2A (0.45) | ALDH1A1MEN1KMT2APOLBHTT | |
| SCHEMBL31649178 | 0.80 | KMT2A (0.45) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL31649429 | 0.79 | CD274 (0.42) | — | |
| SCHEMBL31649428 | 0.79 | KMT2A (0.45) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL31649235 | 0.79 | HTR2A (0.41) | ALDH1A1ADRB2MEN1KMT2ACPS1 | |
| SCHEMBL31649033 | 0.79 | KMT2A (0.36) | ALDH1A1MEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |