SCHEMBL31650732

SCHEMBL31650732

Nc1nccc2c1ccn2[C@H]1C[C@H](O)[C@@H](CO)O1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DNMT1 P26358 2/20 0.50
▸ ADRB1 P08588 1/20 0.50
▸ PNP P00491 1/20 0.48
▸ LMNA P02545 1/20 0.48
▸ TP53 P04637 1/20 0.48
▸ HTT P42858 1/20 0.48
▸ PDE4D Q08499 1/20 0.48
▸ PDE3A Q14432 1/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ RXFP1 Q9HBX9 1/20 0.48
▸ PIM1 P11309 1/20 0.45
▸ CSNK2A2 P19784 1/20 0.45
▸ CSNK2B P67870 1/20 0.45
▸ CSNK2A1 P68400 1/20 0.45
▸ CSNK2A3 Q8NEV1 1/20 0.45
▸ HIF1A Q16665 1/20 0.42
▸ ADA P00813 1/20 0.41
▸ ADORA3 P0DMS8 1/20 0.41
▸ ADORA2A P29274 1/20 0.41
▸ ADORA1 P30542 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1795053 0.86 PNP (0.46) DNMT1ADRB1PNPLMNATP53
2'-Deoxytubercidin SCHEMBL3229680 0.81 METTL3 (0.57) DNMT1ADRB1PNPLMNATP53
2'-Deoxytubercidin SCHEMBL13314431 0.81 METTL3 (0.57) DNMT1ADRB1PNPLMNATP53
2'-Deoxytubercidin SCHEMBL14104716 0.81 METTL3 (0.57) DNMT1ADRB1PNPLMNATP53
2'-Deoxytubercidin SCHEMBL23982116 0.81 METTL3 (0.57) DNMT1ADRB1PNPLMNATP53
2'-Deoxytubercidin SCHEMBL23982321 0.81 METTL3 (0.57) DNMT1ADRB1PNPLMNATP53
2'-Deoxytubercidin SCHEMBL14294692 0.81 METTL3 (0.57) DNMT1ADRB1PNPLMNATP53
2'-Deoxytubercidin SCHEMBL5918830 0.81 METTL3 (0.57) DNMT1ADRB1PNPLMNATP53
SCHEMBL22577638 0.81 ADRB1 (0.50) DNMT1ADRB1PNPLMNATP53
SCHEMBL11021787 0.81 PNP (0.59) DNMT1ADRB1PNPLMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132708-A1 ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF HUNTINGTON'S DISEASE PROQR THERAPEUTICS II B.V. (NL) 2025-06-26 — — WO claimed
WO-2025132708-A1 ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF HUNTINGTON'S DISEASE PROQR THERAPEUTICS II B.V. (NL) 2025-06-26 — — WO disclosed
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