Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15533646 | 0.87 | EPHX2 (0.50) | EPHX2HTR1ASLC6A2HTR2C | |
| SCHEMBL4317786 | 0.85 | MAPT (0.49) | EPHX2HTR1ASLC6A2HTR2CHTR6 | |
| SCHEMBL15533598 | 0.84 | EPHX2 (0.52) | EPHX2HTR1ASLC6A2HTR2C | |
| SCHEMBL1026306 | 0.84 | CYP2C19 (0.57) | EPHX2HTR1ASLC6A2HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL30069211 | 0.82 | LMNA (0.58) | EPHX2HTR1ASLC6A2HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL26600676 | 0.82 | LMNA (0.58) | EPHX2HTR1ASLC6A2HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL30069213 | 0.82 | LMNA (0.58) | EPHX2HTR1ASLC6A2HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL1969103 | 0.82 | LMNA (0.58) | EPHX2HTR1ASLC6A2HTR3EHTR3B | |
| SCHEMBL31651997 | 0.81 | EPHX2 (0.56) | EPHX2HTR1ASLC6A2HTR2C | |
| SCHEMBL2639856 | 0.81 | HTR1A (0.46) | EPHX2HTR1ASLC6A2HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250214977-A1 | STAT6 INHIBITORS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2025-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250214977-A1 | STAT6 INHIBITORS AND USES THEREOF | STAT6, STAT5B, STAT5A | EPHX2 2525/4885CHRNB2 4496/4885CHRNA4 4278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.