SCHEMBL31654522

SCHEMBL31654522

Cc1cncnc1C1CN(C(=O)OC(C)(C)C)C1

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 7/20 0.47
▸ HPGDS O60760 2/20 0.41
▸ KDM4E B2RXH2 1/20 0.40
▸ PDE10A Q9Y233 2/20 0.39
▸ NR1H2 P55055 1/20 0.39
▸ JAK3 P52333 1/20 0.39
▸ HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25888855 1.00 GPR119 (0.47) GPR119HPGDSKDM4EPDE10ANR1H2
SCHEMBL25888789 0.86 GPR119 (0.44) GPR119HPGDSKDM4EPDE10A
SCHEMBL31654410 0.86 GPR119 (0.44) GPR119HPGDSKDM4EPDE10A
SCHEMBL25888707 0.82 GPR119 (0.43) GPR119HPGDSKDM4ENR1H2JAK3
SCHEMBL25888625 0.79 EGLN2 (0.44) GPR119
SCHEMBL31654820 0.79 EGLN2 (0.44) GPR119
SCHEMBL25307351 0.77 GPR119 (0.41) GPR119KDM4E
SCHEMBL30527693 0.77 GPR119 (0.41) GPR119KDM4E
SCHEMBL31654465 0.77 PDE10A (0.47) GPR119KDM4EPDE10ANR1H2JAK3
SCHEMBL25888854 0.77 PDE10A (0.47) GPR119KDM4EPDE10ANR1H2JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A GPR119 399/4885HPGDS 637/4885KDM4E 1488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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