SCHEMBL25888707

SCHEMBL25888707

Cc1ncncc1C1CN(C(=O)OC(C)(C)C)C1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 6/20 0.43
▸ KDM4E B2RXH2 2/20 0.42
▸ IDO1 P14902 1/20 0.40
▸ MAPT P10636 1/20 0.39
▸ THRB P10828 1/20 0.39
▸ NR1H2 P55055 1/20 0.39
▸ ALOX5AP P20292 1/20 0.39
▸ FEN1 P39748 1/20 0.39
▸ HPGDS O60760 1/20 0.39
▸ JAK3 P52333 1/20 0.39
▸ PIK3CA P42336 1/20 0.38
▸ HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30527693 0.85 GPR119 (0.41) GPR119KDM4EIDO1PIK3CA
SCHEMBL25307351 0.85 GPR119 (0.41) GPR119KDM4EIDO1PIK3CA
SCHEMBL25306591 0.84 JAK1 (0.44) GPR119KDM4EIDO1NR1H2ALOX5AP
SCHEMBL26124046 0.83 GPR119 (0.45) GPR119KDM4EIDO1ALOX5APFEN1
SCHEMBL30599815 0.83 GPR119 (0.45) GPR119KDM4EIDO1ALOX5APFEN1
SCHEMBL31654522 0.82 GPR119 (0.47) GPR119KDM4ENR1H2HPGDSJAK3
SCHEMBL25888855 0.82 GPR119 (0.47) GPR119KDM4ENR1H2HPGDSJAK3
SCHEMBL25305154 0.80 GPR119 (0.49) GPR119KDM4EIDO1
SCHEMBL31250355 0.80 GPR119 (0.49) GPR119KDM4EIDO1
SCHEMBL31654410 0.78 GPR119 (0.44) GPR119KDM4EALOX5APFEN1HPGDS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 — — US disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A GPR119 399/4885KDM4E 1488/4885IDO1 1766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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