SCHEMBL25307351

SCHEMBL25307351

COc1ncncc1C1CN(C(=O)OC(C)(C)C)C1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 4/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ SSTR4 P31391 2/20 0.41
▸ PIK3CD O00329 7/20 0.40
▸ IDO1 P14902 1/20 0.39
▸ PIK3CA P42336 2/20 0.39
▸ PIK3CB P42338 2/20 0.39
▸ PIK3CG P48736 2/20 0.39
▸ PDE4B Q07343 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30527693 1.00 GPR119 (0.41) GPR119KDM4ESSTR4PIK3CDIDO1
SCHEMBL25888707 0.85 GPR119 (0.43) GPR119KDM4EIDO1PIK3CA
SCHEMBL25306591 0.81 JAK1 (0.44) GPR119KDM4EIDO1
SCHEMBL26124046 0.81 GPR119 (0.45) GPR119KDM4EIDO1PIK3CA
SCHEMBL30599815 0.81 GPR119 (0.45) GPR119KDM4EIDO1PIK3CA
SCHEMBL29305267 0.78 CYP1A2 (0.38) GPR119SSTR4PIK3CDPIK3CAPIK3CB
SCHEMBL30037992 0.78 CYP1A2 (0.38) GPR119SSTR4PIK3CDPIK3CAPIK3CB
SCHEMBL25309310 0.78 GPR119 (0.47) GPR119KDM4EIDO1PDE4B
SCHEMBL25888629 0.78 PDE4B (0.43) GPR119KDM4EIDO1PDE4B
SCHEMBL31654522 0.77 GPR119 (0.47) GPR119KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 — — US disclosed
EP-4463459-A1 STAT MODULATORS AND USES THEREOF Recludix Pharma, Inc. (US) 2024-11-20 — — EP disclosed
CN-118804917-A STAT modulators and uses thereof 瑞克鲁迪克斯制药股份有限公司 2024-10-18 — — CN disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 — — WO disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A GPR119 399/4885KDM4E 1488/4885SSTR4 1106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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