Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 5/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 5/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 4/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.38 |
| ▸ | HTR3B | O95264 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661207 | 0.72 | ADRB1 (0.38) | ADRB1HTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL23305232 | 0.71 | HTR2A (0.44) | HTR2AHTR2CDRD2SIGMAR1CYP1A2 | |
| SCHEMBL31661187 | 0.70 | ADRB1 (0.43) | ADRB1HTR6DRD2DRD3 | |
| SCHEMBL5371717 | 0.67 | ADRB1 (0.48) | ADRB1HTR2AHTR2CHTR6DRD2 | |
| SCHEMBL31051790 | 0.66 | ADRB1 (0.61) | ADRB1HTR2AHTR6DRD2DRD3 | |
| SCHEMBL31052189 | 0.66 | ADRB1 (0.61) | ADRB1HTR2AHTR6DRD2DRD3 | |
| SCHEMBL5366528 | 0.66 | ADRB1 (0.50) | ADRB1HTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL31052095 | 0.66 | ADRB1 (0.61) | ADRB1HTR2AHTR6DRD2DRD3 | |
| SCHEMBL31052001 | 0.66 | ADRB1 (0.61) | ADRB1HTR2AHTR2CHTR6DRD2 | |
| SCHEMBL31051727 | 0.66 | ADRB1 (0.61) | ADRB1HTR2AHTR6DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151602-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-07-17 | — | — | WO | disclosed |