Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 8/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661179 | 0.80 | CRBN (0.41) | — | |
| SCHEMBL31661222 | 0.75 | HTR3E (0.34) | ADRB1DRD2DRD3DRD4 | |
| SCHEMBL31661169 | 0.74 | MAPKAPK2 (0.38) | ADRB1DRD3HTR6 | |
| SCHEMBL31661183 | 0.70 | ADRB1 (0.46) | ADRB1DRD2DRD3HTR6 | |
| SCHEMBL5371717 | 0.69 | ADRB1 (0.48) | ADRB1DRD2DRD3DRD4HTR6 | |
| SCHEMBL31543858 | 0.68 | CRBN (0.45) | DRD2DRD3DRD4 | |
| SCHEMBL252278 | 0.67 | DRD2 (0.60) | ADRB1DRD2DRD3DRD4HTR6 | |
| SCHEMBL5371496 | 0.64 | ADRB1 (0.58) | ADRB1DRD2DRD3HTR6 | |
| SCHEMBL5373529 | 0.64 | ADRB1 (0.44) | ADRB1DRD2DRD3DRD4HTR6 | |
| SCHEMBL11194827 | 0.64 | DRD2 (0.49) | ADRB1DRD2DRD3DRD4HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151602-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-07-17 | — | — | WO | disclosed |