Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 7/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.38 |
| ▸ | HTR3B | O95264 | 4/20 | 0.38 |
| ▸ | HTR3A | P46098 | 4/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.35 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320385 | 0.78 | TMEM97 (0.36) | SIGMAR1CYP3A4THRBHTR2AHTR2B | |
| SCHEMBL31661205 | 0.75 | QDPR (0.38) | SIGMAR1HTR2CSLC6A4HTR6 | |
| SCHEMBL23305232 | 0.74 | HTR2A (0.44) | SIGMAR1CYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL31661183 | 0.72 | ADRB1 (0.46) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL31661169 | 0.70 | MAPKAPK2 (0.38) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL18537231 | 0.69 | HTR2C (0.40) | HTTHTR2CMAPT | |
| SCHEMBL320709 | 0.69 | TMEM97 (0.38) | SIGMAR1CYP3A4THRBHTR2BMAPT | |
| SCHEMBL5235512 | 0.67 | TGFBR1 (0.51) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL21138067 | 0.67 | IDO1 (0.47) | CYP3A4CYP2C9SLC6A4 | |
| SCHEMBL8259247 | 0.66 | TGFBR1 (0.50) | ADRB1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151602-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-07-17 | — | — | WO | disclosed |