Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.49 |
| ▸ | SKP1 | P63208 | 1/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840531 | 0.82 | HTR1A (0.53) | — | |
| SCHEMBL1059051 | 0.81 | SMARCA2 (0.49) | CKS1BSKP1SKP2 | |
| SCHEMBL8560546 | 0.81 | CKS1B (0.49) | CKS1BSKP1SKP2 | |
| SCHEMBL15985821 | 0.81 | ALDH1A1 (0.45) | CKS1BSKP1SKP2 | |
| SCHEMBL23443530 | 0.81 | FASN (0.51) | — | |
| SCHEMBL6299247 | 0.81 | GBA1 (0.47) | CKS1BSKP1SKP2 | |
| Hydrochloric Acid SCHEMBL6793804 | 0.81 | SMARCA2 (0.48) | CKS1BSKP1SKP2 | |
| SCHEMBL4558301 | 0.80 | BACE1 (0.59) | CKS1BSKP1SKP2 | |
| SCHEMBL6298047 | 0.80 | ACHE (0.44) | CKS1BSKP1SKP2 | |
| SCHEMBL5366552 | 0.78 | TP53 (0.49) | CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114334-A | CENTRAL NERVOUS SYSTEM DISORDERS | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | disclosed |
| EP-0839144-A1 | PIPERAZINE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997003067-A1 | PIPERAZINE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1997-01-30 | — | — | WO | disclosed |