Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | USP1 | O94782 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661573 | 0.95 | PTGS1 (0.41) | NPC1RAB9AL3MBTL1TP53HPGD | |
| SCHEMBL31661647 | 0.91 | NPC1 (0.44) | NPC1RAB9AL3MBTL1TP53HPGD | |
| SCHEMBL31661698 | 0.89 | USP1 (0.38) | NPC1RAB9AL3MBTL1TP53HPGD | |
| SCHEMBL31661606 | 0.88 | RAB9A (0.44) | NPC1RAB9AL3MBTL1TP53HPGD | |
| SCHEMBL31661691 | 0.88 | S1PR1 (0.38) | NPC1RAB9AL3MBTL1TP53MEN1 | |
| SCHEMBL31661543 | 0.87 | S1PR1 (0.45) | NPC1RAB9ATP53NPSR1MEN1 | |
| SCHEMBL31661692 | 0.87 | RAB9A (0.39) | NPC1RAB9AL3MBTL1TP53HPGD | |
| SCHEMBL31661749 | 0.87 | RAB9A (0.38) | NPC1RAB9AL3MBTL1TP53HPGD | |
| SCHEMBL31661537 | 0.87 | NPC1 (0.41) | NPC1RAB9AL3MBTL1TP53HPGD | |
| SCHEMBL31661641 | 0.87 | S1PR1 (0.46) | NPC1RAB9AL3MBTL1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | claimed |
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |