Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | USP1 | O94782 | 3/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661537 | 0.93 | NPC1 (0.41) | S1PR1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL31661770 | 0.92 | S1PR1 (0.43) | S1PR1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL31661698 | 0.91 | USP1 (0.38) | S1PR1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL31661641 | 0.91 | S1PR1 (0.46) | S1PR1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL31661573 | 0.88 | PTGS1 (0.41) | S1PR1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL31661680 | 0.88 | NPC1 (0.38) | S1PR1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL31661647 | 0.88 | NPC1 (0.44) | S1PR1NPC1RAB9ATHRBMEN1 | |
| SCHEMBL31661524 | 0.88 | CA12 (0.39) | S1PR1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL31661565 | 0.87 | THRB (0.47) | S1PR1NPC1RAB9ASMN1; SMN2THRB | |
| SCHEMBL31661764 | 0.87 | RAB9A (0.43) | S1PR1NPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | claimed |
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |