Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ERN1 | O75460 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663182 | 1.00 | ALDH1A1 (0.67) | ALDH1A1LMNAGAASMN1; SMN2RAB9A | |
| SCHEMBL7121916 | 0.87 | SMN1; SMN2 (0.77) | ALDH1A1GAASMN1; SMN2KMT2ATSHR | |
| SCHEMBL11722321 | 0.87 | ALDH1A1 (0.77) | ALDH1A1LMNAGAASMN1; SMN2MAPT | |
| SCHEMBL29486100 | 0.84 | GAA (0.52) | ALDH1A1LMNAGAASMN1; SMN2RAB9A | |
| SCHEMBL2376795 | 0.84 | HPGD (0.53) | ALDH1A1LMNAGAASMN1; SMN2RAB9A | |
| SCHEMBL28746378 | 0.84 | GAA (0.52) | ALDH1A1LMNAGAASMN1; SMN2RAB9A | |
| SCHEMBL2375485 | 0.84 | ALDH1A1 (0.55) | ALDH1A1LMNAGAASMN1; SMN2RAB9A | |
| SCHEMBL4163170 | 0.84 | L3MBTL3 (0.71) | ALDH1A1LMNAGAASMN1; SMN2RAB9A | |
| SCHEMBL3455048 | 0.82 | L3MBTL3 (0.69) | ALDH1A1LMNAGAASMN1; SMN2RAB9A | |
| SCHEMBL19357117 | 0.81 | PHGDH (0.63) | ALDH1A1LMNAGAASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151884-A1 | USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE | PARSONS C LOWELL (US) | 2025-07-17 | — | — | WO | claimed |
| WO-2025151884-A1 | USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE | PARSONS C LOWELL (US) | 2025-07-17 | — | — | WO | disclosed |