SCHEMBL31661727

SCHEMBL31661727

O=C(O)CCCc1ccccc1NC(=O)c1ccc(Br)cc1O

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC16A3 O15427 10/20 0.46
KDM4E B2RXH2 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
MCL1 Q07820 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
MAPK1 P28482 1/20 0.41
NPC1 O15118 3/20 0.41
RAB9A P51151 1/20 0.41
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.40
GAA P10253 1/20 0.40
HTT P42858 1/20 0.40
P2RX1 P51575 1/20 0.40
PPARG P37231 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5657531 1.00 SLC16A3 (0.46) SLC16A3KDM4ETDP1KMT2AMEN1
SCHEMBL28134891 0.83 SLC16A3 (0.52) SLC16A3KDM4ETDP1KMT2AMEN1
SCHEMBL2229279 0.81 SLC16A3 (0.54) SLC16A3KMT2AMEN1MCL1TP53
SCHEMBL31661816 0.81 SMN1; SMN2 (0.53) SLC16A3TDP1KMT2AMEN1NPC1
SCHEMBL31661766 0.81 SLC16A3 (0.54) SLC16A3KMT2AMEN1MCL1TP53
SCHEMBL2061475 0.81 LMNA (0.56) SLC16A3KDM4ETDP1KMT2AMEN1
SCHEMBL31661740 0.81 LMNA (0.56) SLC16A3KDM4ETDP1KMT2AMEN1
SCHEMBL5657282 0.80 SLC16A3 (0.46) SLC16A3NPC1LMNATP53GAA
SCHEMBL31661772 0.80 SLC16A3 (0.46) SLC16A3NPC1LMNATP53GAA
SCHEMBL5657536 0.78 ALOX15 (0.57) MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO claimed
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO disclosed