Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BPTF | Q12830 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661747 | 0.72 | KRAS (0.35) | KRASNPC1RAB9AGAA | |
| SCHEMBL31661745 | 0.72 | KRAS (0.35) | KRASNPC1RAB9AGAA | |
| SCHEMBL31661569 | 0.71 | CYP11B2 (0.37) | — | |
| SCHEMBL240243 | 0.70 | NPC1 (0.52) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL31661742 | 0.69 | KRAS (0.38) | KRASNPC1RAB9AL3MBTL1BPTF | |
| SCHEMBL25763806 | 0.68 | KRAS (0.45) | KRAS | |
| SCHEMBL31661751 | 0.66 | KRAS (0.52) | KRASBPTFALDH1A1GAAHSD17B10 | |
| SCHEMBL15613746 | 0.60 | ADORA2A (0.34) | ALDH1A1MAPK1KDM4E | |
| SCHEMBL20254479 | 0.60 | BPTF (0.51) | KRASL3MBTL1BPTFALDH1A1GAA | |
| SCHEMBL2894690 | 0.60 | NPC1 (0.45) | NPC1RAB9AL3MBTL1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |