Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 3/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 15/20 | 0.34 |
| ▸ | FEN1 | P39748 | 14/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661737 | 0.83 | CYP11B2 (0.32) | CYP11B2 | |
| SCHEMBL31661776 | 0.71 | KRAS (0.36) | — | |
| SCHEMBL2648424 | 0.64 | BPTF (0.44) | — | |
| SCHEMBL27785043 | 0.60 | CYP11B2 (0.66) | CYP11B2ALOX5APFEN1 | |
| SCHEMBL31661745 | 0.58 | KRAS (0.35) | — | |
| SCHEMBL31661747 | 0.58 | KRAS (0.35) | — | |
| SCHEMBL30656371 | 0.56 | ADORA2A (0.63) | CYP11B2ALOX5AP | |
| SCHEMBL26632969 | 0.56 | ADORA2A (0.63) | CYP11B2ALOX5AP | |
| SCHEMBL1422531 | 0.55 | CHRNB2 (0.59) | CYP11B2 | |
| SCHEMBL18255822 | 0.55 | CYP11B2 (0.59) | CYP11B2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | claimed |
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |