Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 5/20 | 0.35 |
| ▸ | USP1 | O94782 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661745 | 1.00 | KRAS (0.35) | KRASUSP1HDAC6HDAC1HDAC8 | |
| SCHEMBL31661613 | 0.83 | GRM5 (0.40) | USP1GRM5NPC1RAB9ALMNA | |
| SCHEMBL31661616 | 0.78 | KRAS (0.59) | KRASUSP1SOS1SCN9A | |
| SCHEMBL31661811 | 0.76 | KRAS (0.43) | KRASUSP1GAAHTTSCN9A | |
| SCHEMBL31661776 | 0.72 | KRAS (0.36) | KRASNPC1RAB9AGAA | |
| SCHEMBL31661633 | 0.72 | CHUK (0.34) | USP1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL31661659 | 0.67 | LMNA (0.55) | NPC1RAB9ALMNAHTTSMN1; SMN2 | |
| SCHEMBL25763806 | 0.66 | KRAS (0.45) | KRASSOS1 | |
| SCHEMBL31661742 | 0.65 | KRAS (0.38) | KRASNPC1RAB9ASOS1GAA | |
| SCHEMBL31661762 | 0.63 | NR1H4 (0.50) | NPC1RAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | claimed |